Phytochemical analysis ofAchillea ligusticaAll. from Lipari Island (Aeolian Islands)

A comprehensive phytochemical analysis of Achillea ligustica All. from Lipari Island, part of the UNESCO-listed Aeolian Islands, revealed 17 unique metabolites, including sesquiterpenoids and flavonoid glucuronides not previously documented in this species. The study identified compounds such as (3RS,6RS)-2,6-dimethyl-1,7-octadiene-3,6-diol and iso-seco-tanapartholide from dichloromethane extracts, alongside novel flavonoid glucuronides like apigenin-7-O-glucuronide and quercetin 3-O-glucuronide. These findings suggest a chemotaxonomic significance for the species, with similarities to populations in Greece, Sicily, and Algeria. The research employed GC/MS analysis on petroleum ether extracts and isolated metabolites from aerial parts and flowers, providing new insights into the chemical diversity of Achillea ligustica.

Venditti, A., Guarcini, L., Bianco, A., Rosselli, S., Bruno, M., & Senatore, F. (2015). Phytochemical analysis ofAchillea ligusticaAll. from Lipari Island (Aeolian Islands). Natural Product Research, 30(8), 912–919. https://doi.org/10.1080/14786419.2015.1079188