Recombination rate variation in mice from an isolated island

A study on wild house mice from Gough Island reveals significant variation in recombination rates, with some genomic intervals showing up to 28% divergence. Despite this high level of polymorphism, the genomewide recombination rate remains stable. Researchers analyzed genetic maps from 1212 meioses and compared them to a mainland reference strain, uncovering that recombination rate variation is more pronounced at smaller genomic scales. The findings suggest that most evolutionary changes occurred in one line of Gough Island mice, highlighting the complex nature of recombination rate evolution across different genomic regions.

Wang, R. J., Gray, M. M., Parmenter, M. D., Broman, K. W., & Payseur, B. A. (2016). Recombination rate variation in mice from an isolated island. Molecular Ecology, 26(2), 457–470. Portico. https://doi.org/10.1111/mec.13932